The abortive infection functions of CRISPR-Cas and Argonaute
Authors
: Yu Chen, Zhifeng Zeng, Qunxin She and Wenyuan Han
Trends in Microbiology.
30 Nov 2022.
Article: CRISPR-Cas and prokaryotic Argonaute (pAgo) are nucleic acid (NA)-guided defense systems that protect prokaryotes against the invasion of mobile genetic elements. Previous studies established that they are directed by NA fragments (guides) to recognize invading complementary NA (targets), and that they cleave the targets to silence the invaders.CRISPR-Cas and prokaryotic Argonaute (pAgo) are nucleic acid (NA)-guided defense systems that protect prokaryotes against the invasion of mobile genetic elements. Previous studies established that they are directed by NA fragments (guides) to recognize invading complementary NA (targets), and that they cleave the targets to silence the invaders.
Full article:https://www.sciencedirect.com/science/article/pii/S0966842X22003134
